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IL2 Receptor beta 抗体

This anti-IL2 Receptor beta antibody is a 大鼠 单克隆 antibody detecting IL2 Receptor beta in FACS, IP 和 Func. Suitable for 小鼠.
产品编号 ABIN120200
发货至: 中国

Quick Overview for IL2 Receptor beta 抗体 (ABIN120200)

抗原

See all IL2 Receptor beta (IL2RB) 抗体
IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This IL2 Receptor beta antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

克隆位点

TM-BETA1
  • 特异性

    This antibody recognises the CD122 cell surface glycoprotein. Clone TM-beta 1 is reported to block IL-2 high affinity binding to the IL-2R beta receptor. We recommend the use of SM2224LE for this purpose.

    纯化方法

    Affinity chromatography on Protein G

    内毒素水平

    Low Endotoxin

    免疫原

    Cells from murine IL-2RB+ transformant TART-mBeta. Lymph node (cells from immunised Sprague Dawley rats were fused with cells of the mouse PA1 myeloma cell line.

    亚型

    IgG2b
  • 应用备注

    Flow Cytometry: 1/10 - 1/50, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation. Functional Assays.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.4

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody at -20 °C to -70 °C.
  • 抗原

    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

    别名

    CD122 / IL2RB

    背景

    CD122 is a 75-85kD molecule also known as interleukin-2 receptor (IL-2R) beta chain. In mouse, CD122 is primarily expressed on natural killer (NK) cells and at lower levels on lymphocyte subsets, monocytes and macrophages. CD122 can associate with the IL-2R alpha chain (CD25) and CD132 to form a functional high affinity receptor complex that binds IL-2. CD132/CD122 heterodimers can also be formed which bind IL-2 with intermediate affinity. IL-2 binding to the IL-2R is important in the generation and differentiation of T lymphocytes and NK cells.Synonyms: IL-2 receptor subunit beta, IL2 Receptor beta, Interleukin-2 receptor subunit beta, P70-75

    基因ID

    16185

    NCBI登录号

    NP_032394

    UniProt

    P16297

    途径

    JAK/STAT Signaling, Growth Factor Binding
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